Extended Data Figure 3: Individuals who share a household at present or have shared one in the past have significantly similar microbiomes.
From: Environment dominates over host genetics in shaping human gut microbiota
First-degree relatives and individuals with present household sharing have significantly similar species and bacterial gene abundances (P < 0.01; permutation testing). a–c, Box plots depict the distribution of Bray–Curtis dissimilarities across pairs of individuals at the phylum (a), species (b) and bacterial genes (c) level. Each panel shows the Bray–Curtis dissimilaries among all pairs of (i) first-degree relatives, who are likely to have experienced present or past household sharing (n = 55 pairs); (ii) second-to-fifth-degree relatives, who are unlikely to have experienced present or past household sharing (n = 24 pairs); (iii) unrelated individuals self-reported to currently share a household (n = 32 pairs); and (iv) all other individuals (n = 255,891 pairs). The lower and upper limits of the boxes represent the 25% and 75% percentiles, respectively, and the top and bottom whiskers represent the 5% and 95% percentiles, respectively. The P value ranges for all panels are: **P < 0.01 and ***P < 0.005.
