Extended Data Figure 7: Expression of markers of IPCs in the developing PFC.
From: A single-cell RNA-seq survey of the developmental landscape of the human prefrontal cortex
a, Heat map of differentially expressed genes in EOMES+ NPCs at GW10 and GW16. Expression of known genes at each stage is shown to the right of each heat map panel with enriched gene ontology terms. n = 288 cells. b, Heat map of expression of cell-cycle genes in all NPCs and neurons. The pie chart at the bottom indicates the ratios of cell types at each cell-cycle stage. c, Gene expression of novel markers of IPCs across developmental time corresponding to human cortical neurogenesis. NPCs: GW8, 3 cells; GW9, 50 cells; GW10, 84 cells; GW12, 12 cells; GW13, 7 cells; GW16, 123 cells; GW19, 5 cells; GW23, 2 cells; GW26, 4 cells. d, The expression of novel markers of IPCs is shown using the same layout as Extended Data Fig. 2b (grey, no expression; yellow–red, relative expression). n = 288 NPCs.
