Extended Data Figure 9: Whole-cell patch-clamp recordings in the developing PFC.
From: A single-cell RNA-seq survey of the developmental landscape of the human prefrontal cortex
a, Immunostaining after whole-cell patch-clamp recordings of the PFC at GW23. Scale bar, 100 μm. n = 3 independent replicates. b, Whole-cell patch-clamp recordings of the PFC at GW23. c, Quantification of Na+ current (top) and K+ current (bottom) of neurons located in upper layer, deep layer or subplate of GW23 PFC. n = 31 neurons from three independent replicates. Data are mean ± s.e.m. All P > 0.05, two-way ANOVA. d, Whole-cell patch-clamp recordings of the PFC neurons at GW26. e, Immunostaining after whole-cell patch-clamp recordings of the PFC neurons at GW26. Scale bar, 100 μm. f, Three-dimensional reconstructions of neurons are shown. Scale bar, 30 μm. Nine representative images are shown from n = 26 neurons from three independent replicates.
