Extended Data Figure 4: Relative expression of known markers of each cell type.
From: A single-cell RNA-seq survey of the developmental landscape of the human prefrontal cortex
a, The bifurcation of gene expression along two branches is clustered hierarchically into six modules. Gene ontology analysis of each module reflected the processes controlling neuronal and glial fate commitment. In this heat map, columns are points in pseudo-time, rows are genes and the middle (NPCs) is the beginning of pseudo-time. One lineage goes from the middle of the heat map to the right (glial cells) while the other lineage goes to the left (excitatory neurons). n = 1,540 cells. b, The markers (EOMES, HES1 for NPCs; NEUROD1, NEUROD6, SLA for excitatory neurons; GFAP, S100B for astrocytes; OLIG2, PDGFRA for OPCs) were ordered by Monocle analysis in pseudo-time as in Fig. 1c; the shadow indicates the confidence interval around the fitted curve.
