Hierarchical models provide reliable statistical estimates for data sets from high-throughput experiments where measurements vastly outnumber experimental samples.
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Ji, H., Liu, X. Analyzing 'omics data using hierarchical models. Nat Biotechnol 28, 337–340 (2010). https://doi.org/10.1038/nbt.1619
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DOI: https://doi.org/10.1038/nbt.1619
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