Figure 2: Divergence rate and selective sweep regions. | Nature Biotechnology

Figure 2: Divergence rate and selective sweep regions.

From: Genome sequencing and comparison of two nonhuman primate animal models, the cynomolgus and Chinese rhesus macaques

Figure 2

(a) The genetic distance between macaques (blue curve), human and macaques (red curve), and the distance between macaque species/subspecies (green curve for IR and CR; yellow curve for CR and CE) across chromosome 14. The dashed red line depicts the average genetic distance between human and macaque. The dotted blue line represents the average genetic distance between the macaques. The red bars at the bottom denote the candidate selective sweep regions, and the blue bars denote the putative introgression regions. The consecutive regions containing zero mutations in all species (such as the ∼20 Mb region) are sequencing gaps or alignment gap regions. (b) A potential introgression region (shaded blue), which contains fewer variations between CE macaque and CR macaque than between the two rhesus macaques (IR macaque and CR macaque). (c) A selective sweep region, encompassing 400 kb, which contains only one gene. The red bar denotes the coding region of the SBF2 gene; the red shaded box corresponds to the extent of the putative selective sweep.

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