Table 1 Recent patent applications in optogenetics
Patent number | Description | Assignee | Inventor | Priority application date | Publication date |
|---|---|---|---|---|---|
US8733290B2 | A system for providing an interface for interacting with a laboratory animal, including providing a laboratory animal implanted with electrode connectors, placing the animal into an animal cage coupled to a system and interacting with the animal with a device such as an infusion pump, laser source, telemetry transmitter, biopotential monitoring device or brain stimulating device. The system provides the capability of a fiberoptic interface in combination with an electroencephalogram interface in freely moving animals. | Gerashchenko L | Gerashchenko L | 4/3/2012 | 5/27/2014 |
US20140064654A1 | An optical fiber-based beam scanning apparatus that enables focusing of the output beam at any point within a three-dimensional scan region; well suited for applications including imaging, confocal microscopy, optical trapping, sensing, biomarker interrogation, two-dimensional microscopy, three-dimensional microscopy, targeted light delivery for optogenetics and optical communications. | Board of Trustees of Stanford University (Palo Alto, CA, USA) | Anand KJB, Solgaard O, Kahn JM, Jan C | 8/31/2012 | 3/6/2014 |
WO2014028451A1 | A method for changing the permeability of endothelial cells, comprising either contacting endothelial cells expressing optogenetic reagents with light, where the light activates optogenetic reagents; or (i) infecting endothelial cells with recombinant viruses comprising a recombinant nucleic acid encoding an optogenetic reagent to produce infected endothelial cells, and (ii) contacting the infected endothelial cells with light. | Brown University (Providence, RI, USA) | Brown TC, Moore CI | 8/13/2012 | 2/20/2014 |
KR1339412B1 | Gallium nitride light-emitting diode (GaN LED) device for optogenetics. Fabrication involves separating a LED device, formed on a sacrificial substrate, from the sacrificial substrate. The separated LED device is transferred to a plastic substrate. Preferably, the separation of the LED device from the sacrificial substrate is performed by a laser beam lift-off method in which a laser beam is irradiated on the rear surface of the sacrificial substrate. | Korea Advanced Institute of Science and Technology (Daejon, S. Korea) | Lee KJ, Park SY, Lee SH, Park Kl, Koo M | 10/22/2012 | 12/10/2013 |
US20130261506A1 | Systems and methods for noninvasive neuromodulation using ultrasound for the diagnosis or treatment of post-traumatic stress disorder; can be used in combination with or substituted for ultrasound transducers that are selected from the group consisting of transcranial magnetic stimulation, deep-brain stimulation, transcranial direct current stimulation, optogenetics application, radiosurgery, radio-frequency therapy and medications. | Mishelevich DJ | Mishelevich DJ | 3/27/2012 | 10/3/2013 |
WO2013059833A1 | Method involving directing acoustic energy to an individual's brain through an individual's cranium to produce cognitive effect; can be used for communication in addition to or instead of transcranial magnetic stimulation, transcranial direct current stimulation, transcranial alternating current stimulation, targeted electrical stimulation, deep brain stimulation, one electrode or an array of electrodes implanted on the surface of the brain or dura, and light activation of specially engineered proteins. | Neurotrek (Los Gatos, CA, USA), Tyler WJ, Goldwasser I, Muratore R, Pal S, Sato T, Wetmore DZ | Tyler WJ, Goldwasser I, Muratore R, Pal S, Sato T, Wetmore DZ | 10/21/2011 | 4/25/2013 |
GB2480640A | The use of light-deflective particles in the amplification or enhancement of a luminescent signal within a high scattering medium; the optical enhancer beads are taken up by cells to be grafted into a recipient to facilitate transduction of optical signals, used, for example, in phototherapy and optogenetics. | University of Antwerp (Antwerp, Belgium) | De Vocht N, Van der Linden A-M, Ponsaerts P, Berneman ZN, De Visscher G | 5/26/2010 | 11/30/2011 |
