Table 1 Recent patent applications in single cell analysis
Patent number | Description | Assignee | Priority application date | Publication date |
|---|---|---|---|---|
US20150004687A1 | A cell capture device with an inflow tube and an inflow port arranged in a position outside the observation area, when viewed from the normal line direction of the filter. Useful for capturing circulating tumor cells contained in peripheral blood. | Hitachi Chemical Company (Tokyo), Tokyo University of Agriculture and Technology (Tokyo) | 1/5/2012 | 1/1/2015 |
US8906669B2 | A sequential flow microfluidic device with a capture chamber allowing particles provided within the fluid to be collected, and a method for effecting cell or molecular analysis. For use in biomimetic analysis and sample treatment of a fluid in a living organism. | Dublin City University (Dublin), Dimov I, Kijanka G, Lee L, Ducree J | 10/9/2009 | 12/9/2014 |
US20140356884A1 | A microfluidic device comprising a first fluidic channel, a second fluidic channel, a discontinuously porous membrane having pores and binding moieties; useful for capturing particles, e.g., mammalian or bacterial cells. | Mittal S, Toner M | 8/23/2011 | 12/4/2014 |
US8889168B2 | Biocompatible stem cell capture and immobilization coatings comprising a solid surface having a film of nonpolar liquid disposed on it. Useful as, e.g., medical implant devices and scaffolds for tissue growth and bone growth. | Spedden RH, Bioactive Surgical (Clarksville, MD, USA), Borch W, Qiu J | 8/7/2008 | 11/18/2014 |
US20140335604A1 | A device for staining suspended cells composed of a cannula, a pushrod, a plunger sealing pad and a capture membrane; for use in staining suspended cells, effectively overcoming the drawbacks in current existing methods, such as high failure rates, low accuracy and repeatability, and being very time-consuming. | Wuhan Cell Marker & Machine Tech. Co. (Hubei, China) | 10/19/2011 | 11/13/2014 |
US8837802B2 | An image analysis system with an acquisition module, image capturing module and multispectral image-reproduction module to re-treat a sharpened enlarged image of a suspected cancerous cell captured from the capturing unit. Useful for identifying cancerous cells. | Jen C-P, Wang H-C, National Chung Cheng University (Chiayi, Taiwan), Lin T-C, Huang C-T, Hsiao J-H, Chien T-W | 3/12/2012 | 9/16/2014 |
EP2771667A1 | A sample transfer apparatus with an accelerator chamber with an entrance end spaced out from the discharge end of a decelerator tube, and an outlet end that is displaced downstream of the entrance end to define a flow acceleration channel; useful for mass cytometry. | Fluidigm Canada (Markham, Ontario, Canada) | 10/26/2011 | 9/3/2014 |
EP2769204A2 | A cell capture system comprising a fluid-permeable, planar membrane comprising an exposed first surface and a register associated with the membrane that permits the determination of the location of cells retained on at least a portion of the planar membrane. Used in determining the presence and/or amount of cells, for example, viable cells, in a liquid sample. | Charles River Laboratories (Wilmington, MA, USA), ReaMetrix (San Carlos, CA, USA) | 5/2/2012 | 8/27/2014 |
EP2739587A1 | A cell capture system with an outlet manifold that is defined on the broad face of a substrate and connected to an outlet channel. | Denovo Sciences (Plymouth, MI, USA) | 8/1/2011 | 6/11/2014 |
US20140154703A1 | A microfluidic device comprising an input, an output, and an array of obstacles disposed between it and further comprising support pillars; useful for enriching circulating tumor cells. | Skelley A, Smirnov D, Dong Y, Merdek K, Sprott K, Carney W, Jiang C, Huang R, Lupascu I | 1/6/2011 | 2/20/2014 |
