Supplementary Figure 1: Characterization of OKSM-iNSCs
From: Lineage conversion induced by pluripotency factors involves transient passage through an iPSC stage
(A) Gene expression levels of Sox1 and Sox2 in the indicated cell types by microarray gene expression analysis. (B) Dendrogram cluster analysis of global gene expression of indicated samples by expression microarrays. (C) Scatter plot analysis shows linear regression coefficient (R2) of global gene expression by microarray analysis between MEFs and OKSM-iNSCs and brain-derived NSCs and OKSM-iNSCs, respectively. (D) Functional annotation analysis of upregulated genes (2-fold or more) in OKSM-iNSCs vs. MEFs by gene expression microarray. Top categories are shown together with the number of genes and Benjamini-Hochberg-corrected p-value. (E) Gene expression levels of Nanog in the indicated cell types by microarray analysis.
