Papers from the literature selected by the Nature Biotechnology editors. (Follow us on Twitter, @NatureBiotech #nbtHighlight)

Highly parallel genome-wide expression profiling of individual cells using nanoliter droplets

Macosko, E.Z. et al. Cell 161, 1202–1214 (2015)

Droplet barcoding for single-cell transcriptomics applied to embryonic stem cells

Klein, A.M. et al. Cell 161, 1187–1201 (2015)

Effect of predicted protein-truncating genetic variants on the human transcriptome

Rivas, M.A. et al. Science 348, 666–669 (2015)

Comprehensive serological profiling of human populations using a synthetic human virome

Xu, G.J. et al. Science 10.1126/science.aaa0698 (5 June 2015)

A microfluidic device for label-free, physical capture of circulating tumor cell clusters

Sarioglu, A.F. et al. Nat. Methods 10.1038/nmeth.3404 (18 May 2015)