Supplementary Figure 6: Overlap between OQs in K⁺ and Na⁺ + PDS conditions.

a) Venn diagram showing the overlap between the two conditions. The numbers in brackets at the top indicate the total OQs detected in K⁺ (525,890) and Na⁺+PDS (716,310); the percentages on the side (27% and 46%) indicate the OQs detected exclusively by either condition; the percentages in the middle overlapping both circles indicate OQs detected by both conditions, as percentage of total K⁺ OQs (73%) or total PDS OQs (54%). The 27% OQs detected solely in K⁺ displayed an average mismatch percentage of ~18.5% in PDS (panel b); the 46% OQs detected solely in PDS displayed an average mismatch percentage of ~10% in K⁺ (panel c). The average mismatch percentage of randomly selected genomic locations is below 2%. b) Mismatches for OQs detected in K⁺ only (27% subset in the Venn diagram). c) Mismatches for OQs detected in PDS only (46% subset in the Venn diagram). In both b) and c), red lines indicate the thresholds set for the two data sets, 18% for K⁺ and 25% for PDS (Methods).