Supplementary Figure 12: Relative abundances of 12 species exhibiting significant differences.

The bacterial species whose relative abundances are above 0.1% in any sample were used in a Wilcoxon test to demonstrate the impact of (a) provider (b) housing laboratory (c) strain (d) diet and (e) gender (see supplementary table S1) on the mouse gut microbiome. The test results were adjusted for FDR. “***” indicates p-value ≰ 0.001, “**”indicates p-value ≰ 0.01, “*”indicates p-value ≰ 0.05, “NS” indicates p-value ≱ 0.05. The “provider” markedly affects Lactobacillus johnsoni to different degrees comparing G8 and G9; “strain” differentially affects Bacteroides intestinalis and Bacteroides vulgatus comparing G2, G3 and G4; and diet significantly affects Akkermansia muciniphila, Bacteroides intestinalis, Bacteroides vulgatus and Lactobacillus johnsoni comparing G13, G14 and G15.