Supplementary Figure 9: First iteration of REVEALER for the KRAS-dependency example.
From: Characterizing genomic alterations in cancer by complementary functional associations
A) The target profile is a profile relative KRAS-dependence and the seed feature is the mutation status of KRAS. REVEALER identifies a copy number gain across a region on chromosome 8q23-24 (feature NSMCE2_AMP) as the most complementary genomic alteration to KRAS mutation. B) The clustered version of the same top scoring features shown in A.
