Supplementary Figure 2: Second iteration of REVEALER for the β-catenin activation in cancer example. | Nature Biotechnology

Supplementary Figure 2: Second iteration of REVEALER for the β-catenin activation in cancer example.

From: Characterizing genomic alterations in cancer by complementary functional associations

Supplementary Figure 2

A) Conditioning to the summary feature after the first iteration, consisting of the seed feature (β-catenin mutation: CTNNB1.MC_MUT) and APC mutation (APC.MC_MUT), REVEALER finds amplifications in 13q33 (feature ITGBL1_AMP) as the best match. B) The clustered version of the same top scoring features shown in A.

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