Supplementary Figure 3: Consumption of a diet devoid of one essential amino acid causes a drop of the corresponding EAA in the plasma. | Nature Biotechnology

Supplementary Figure 3: Consumption of a diet devoid of one essential amino acid causes a drop of the corresponding EAA in the plasma.

From: Regulating the expression of therapeutic transgenes by controlled intake of dietary essential amino acids

Supplementary Figure 3

Following an overnight fasting period, AARE-Luc transgenic mice were fed for 6 hours, a control diet (Ctrl) or a diet devoid of alanine (-Ala), or histidine (-His), or isoleucine (-Ile), or methionine (-Met), or leucine (-Leu), or lysine (-Lys), or phenylalanine (-Phe), or threonine (-Thr), or tryptophan (-Trp), or valine (-Val). At the end of the experiments, blood was collected and amino acid measurement was performed for the different nutritional conditions (Student's t-test: ***p <0.001, n=6 male mice; error bars: means ± s.e.m.).

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