Supplementary Figure 5: Impact on hematopoietic progenitors | Nature Biotechnology

Supplementary Figure 5: Impact on hematopoietic progenitors

From: Non-genotoxic conditioning for hematopoietic stem cell transplantation using a hematopoietic-cell-specific internalizing immunotoxin

Supplementary Figure 5

Immunophenotypic assessment of myeloid progenitors, granulocyte macrophage progenitors (GMP), common myeloid progenitors (CMP), megakaryocyte erythroid progenitors (MEP) and common lymphoid progenitors (CLP) in the bone marrow of C57BL/6 mice, 2 and 6 days after conditioning with 5Gy TBI or 3 mg/kg CD45-SAP. Data represent mean percentage relative to untreated control ± SEM (n = 6 mice/group, n = 3 mice per time point assayed individually). * indicates p value <0.05; ** indicates p value <0.01; *** indicates p value <0.001; n.s. indicates not significant (p value >0.05). Statistics calculated using two-sided unpaired t test.

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