Supplementary Figure 7: Effects on non-hematopoietic marrow composition | Nature Biotechnology

Supplementary Figure 7: Effects on non-hematopoietic marrow composition

From: Non-genotoxic conditioning for hematopoietic stem cell transplantation using a hematopoietic-cell-specific internalizing immunotoxin

Supplementary Figure 7

Composition of the non-hematopoietic bone marrow compartment 2 days post 3 mg/kg CD45-SAP or 5Gy TBI vs untreated control C57BL/6 mice. Enzymatically-dissociated marrow and bone-associated cells were characterized by immunophenotype with non-hematopoietic stromal and endothelial cells defined as CD45- Ter119- CD31- and CD45- Ter119- CD31+, respectively. Data represent mean ± SEM (n = 5 mice/group, assayed individually). * indicates p value <0.05; ** indicates p value <0.01; *** indicates p value <0.001; n.s. indicates not significant (p value >0.05). Statistics calculated using two-sided unpaired t test.

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