Supplementary Figure 12: Activity of anti-human CD45 immunotoxins | Nature Biotechnology

Supplementary Figure 12: Activity of anti-human CD45 immunotoxins

From: Non-genotoxic conditioning for hematopoietic stem cell transplantation using a hematopoietic-cell-specific internalizing immunotoxin

Supplementary Figure 12

CD45-SAP immunotoxins created from anti-human anti-CD45 monoclonal antibody clones MEM-28 and HI30 induce Jurkat cell death in vitro (72 hour incubation) with IC50 values of 130 and 200 pM, respectively; Data represents mean ± SD (n = 3 technical replicates) of a representative experiment.

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