Supplementary Figure 1: Quantification of endogenous Htt mRNA by qPCR.

WT: wild type mice; Q20: HET mice from HdhQ20line; Q50: HET mice from HdhQ50 line; Q80: HET mice from HdhQ80line; Q92: HET mice from HdhQ92 line; Q111: HET mice from HdhQ111 line; Q140: HET mice from CAG 140 KI line; Q175: HET mice from zQ175 line; Q50neo: HET mice from HdhQ50neo in line. Asterisk (*) denote significant differences of the levels of mRNA of the endogenous Htt against the WT controls. Number symbols (#) denote significant differences of the levels of mRNA of the endogenouse Htt from HET mice from Q50 line against the HET mice from all the other lines. Data are expressed as mean + S.E.M. n=4-8 per group.