Supplementary Figure 2: Methylation State of Age-related CpGs in iPSCs and PBMCs
From: Influence of donor age on induced pluripotent stem cells
This heatmap depicts the methylation state of CpGs that are predictive of biological age and are displayed for iPSCs and PBMCs of donors across all ages. Blue indicates methylated CpGs while red indicates unmethylated CpGs. CpGs are clustered based on their methylation pattern and samples are ordered by sample type (iPSC vs. PBMC) and donor age. Note that many iPSC CpG sites are strongly de-methylated (bright red) whereas CpG sites shift to intermediate methylation (yellow/orange) across older individuals.
