Supplementary Figure 11: in vivo electrophysiological properties of P1S5D grafted neurons. | Nature Biotechnology

Supplementary Figure 11: in vivo electrophysiological properties of P1S5D grafted neurons.

From: Combined small-molecule inhibition accelerates the derivation of functional cortical neurons from human pluripotent stem cells

Supplementary Figure 11

(a, b) Recordings of action potentials and firing patterns as well as sEPSCs from a GFP+ graft at P10 (a) and P30 (b), respectively, with unusually mature properties. (c,d) Most GFP+ cells in grafts exhibited more immature firing patterns as illustrated by representative action potentials in c and sEPSCs in d recorded at P15 and P45. N = 4 animals for P1S5D condition analyzed, and 1 animal for P8S10 condition analyzed.

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