Supplementary Figure 7: Dysregulated protein–protein associaction networks in basal-subtype breast cancer cell lines. | Nature Biotechnology

Supplementary Figure 7: Dysregulated protein–protein associaction networks in basal-subtype breast cancer cell lines.

From: Detection of dysregulated protein-association networks by high-throughput proteomics predicts cancer vulnerabilities

Supplementary Figure 7

Proteins with dysregulated protein-protein associations are shown in red on the entire network of all protein-protein associations defined through co-regulation analysis (Fig. 2, Supplementary Table 6). Association dysregulations were determined by bivariate outlier detection of deviations of co-regulation of any protein pair across 41 breast cancer cell lines calculating the Mahalnobis distance and using the Grubb’s outlier test (p<0.1, Supplementary Table 8).

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