Supplementary Figure 8: No substantial C-to-T editing was detected in the region outside of the spacer | Nature Biotechnology

Supplementary Figure 8: No substantial C-to-T editing was detected in the region outside of the spacer

From: Base editing with a Cpf1–cytidine deaminase fusion

Supplementary Figure 8

(a) Schematic diagram illustrating the PAM region, the 20-nt region upstream of PAM and the 20-nt region downstream of spacer. (b) The C-to-T editing frequencies of the indicated cytosines outside of the spacer region were individually determined at the indicated sites. 293FT cells were either treated with dCpf1-BE (purple) or non-transfected (gray) before deep sequencing. Means ± s.d. were from three independent experiments.

Back to article page