Supplementary Figure 4: Weak relation between cytokine connectivity degrees and historical knowledge accumulation. | Nature Biotechnology

Supplementary Figure 4: Weak relation between cytokine connectivity degrees and historical knowledge accumulation.

From: Immune-centric network of cytokines and cells in disease context identified by computational mining of PubMed

Supplementary Figure 4

The correlation of the cytokine degree and the date of first publication was repeatedly computed across cytokines, threshold by minimal degree. A scatter plot showing this correlation when scaled back from the entire network to only few highly dominant hubs (cytokine degree cutoff is shown along x-axis). The entire network (n=145 cytokines) demonstrates low correlation, r=-0.27 and -0.26, Pearson's for (a) incoming and (b) outgoing interactions respectively, driven by a few highly dominant hubs.

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