Supplementary Figure 3: Indel analysis on the rhPCSK9 targeted locus by deep sequencing of PCR amplicons.
From: Meganuclease targeting of PCSK9 in macaque liver leads to stable reduction in serum cholesterol
DNA isolated from liver biopsy sample was used as template for PCR (251 bp amplicon indicated as 1; 417 bp amplicons indicated as 2) and deep sequencing analysis. DNA isolated from each animal’s PBMCs (collected before study) served as a control.
