Supplementary Figure 7: C101S and C106S mutations of hA3A eliminated the editing activity of hA3A-BE3.
From: Efficient base editing in methylated regions with a human APOBEC3A-Cas9 fusion
Base editing frequencies induced by hA3A-BE3, hA3A-BE3-C101S (a) and hA3A-BE3-C106S (b) on indicated cytosines at seven different genomic loci. These data show that C101S and C106S mutations of hA3A eliminated the editing activity of corresponding BEs. Means ± s.d. were from three independent experiments.
