Supplementary Figure 10: Monte Carlo simulation of fluorosequencing closely matches the experimentally observed error distribution. | Nature Biotechnology

Supplementary Figure 10: Monte Carlo simulation of fluorosequencing closely matches the experimentally observed error distribution.

From: Highly parallel single-molecule identification of proteins in zeptomole-scale mixtures

Supplementary Figure 10

(A) Experimental sequence histograms of GC♦AGC♦AGAG (A, left panel) and its N-acetylated control (A, middle panel) replotted from Fig. 4B for easy comparison. (B) Simulated fluorosequencing of GC♦AGC♦AGAG with errors (B, right panel) and its N-acetylated control (B, middle panel) result in observed (simulated) signal (B, left panel) that closely matches observed experimental data in A. ♦indicates Atto647N conjugated to cysteine.

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