Table 1 Recent patent applications in antibodies
Patent # | Subject | Assignee(s) | Inventor(s) | Priority application date | Publication date |
|---|---|---|---|---|---|
US 20070266448, WO 2007131676 | Producing a human monoclonal antibody from an immunodeficient nonhuman animal for preparing a composition for treating cancer, by collecting from the reconstituted animal a human cell producing human antibody against an antigen. | Hoffmann La Roche (Basel), Lifke A, Lifke V, Mueller-Beckmann B, Schnitzer T | Lifke A, Lifke V, Mueller-Beckmann B, Schnitzer T | 5/11/2006 | 11/15/2007, 11/22/2007 |
DE 202007009011 | A point-of-care device for detecting antiaprotinin antibodies in a liquid sample, comprising a sample application zone, a reaction zone and a detection zone, one of which contains aprotinin; useful for determining the presence or concentration of antiaprotinin antibodies, which can cause allergic reactions in patients treated with aprotinin, e.g., to reduce bleeding during heart surgery. | CellTrend (Luckenwalde, Germany) | – | 6/22/2007 | 11/8/2007 |
WO 2007126799 | An isolated human or humanized antibody or functional fragment comprising an antigen-binding region that is specific for target protein c-Met, where the antibody or functional fragment binds to c-Met. | Novartis (Basel), Novartis Pharma (Vienna) | Berger C, Brocks B, Prassler J, Stover DR | 3/30/2006 | 11/8/2007 |
WO 2007123697 | A cocktail of antibodies to the HMW-MAA protein comprising two antibodies, each recognizing a distinct epitope on the HMW-MAA protein; useful for treating cancer, e.g., melanoma or sarcoma. | John Wayne Cancer Institute (Santa Monica, CA, USA) | Ferrone S, Goto Y, Hoon DSB, Kitago M | 3/29/2006 | 11/1/2007 |
WO 2007123737 | A viral vector comprising a nucleic acid encoding an anti-cytotoxic T-lymphocyte antigen-4 (CTLA-4) antibody capable of binding to extracellular domain of CTLA-4 and inhibiting CTLA-4 signaling. | University of California (Berkeley, CA, USA) | Allison J, Curran M | 3/30/2006 | 11/1/2007 |
WO 2007122517, CA 2541872, CA 2586302 | Detecting the presence or absence of influenza antibodies in a sample, comprising contacting the sample with a hemagglutinin pseudotyped virus under conditions to form an immune complex, and detecting the presence or absence of the immune complex formed. | Institut Pasteur (Paris), Institut Pasteur du Cambodge (Phnom Pen, Cambodia), HKUPasteur Research Centre (Hong Kong, PRC), Altmeyer R, Buchy P, Garcia J, Nefkens I, Peiris M | Altmeyer R, Buchy P, Garcia J, Nefkens I, Peiris M | 4/26/2006 | 11/1/2007, 10/26/2007, 10/26/2007 |
US 20070237776, WO 2007117577 | An agent capable of specifically binding human interleukin 18 receptor alpha, comprising a light chain variable region or a heavy chain variable region; useful to treat, e.g., sepsis, liver injury and inflammatory bowel diseases. | Regeneron Pharmaceuticals (Tarrytown, NY, USA), Fairhurst JL, Huang TH, Huang TT, Karow M, Martin JH, Mikulka WR, Pobursky KJ, Stevens S, Windsor JA | Fairhurst JL, Huang TH, Huang TT, Karow M, Martin JH, Mikulka WR, Pobursky KJ, Stevens S, Windsor JA | 4/7/2006 | 10/11/2007, 10/18/2007 |
CN 200962112 | A kit for testing types of porcine circovirus (PCV) antibodies that has a detecting plate whose envelope actigen is an adopted recombinant expression PCV2 pitted framing-signal capsid protein, which retains the antigen of the integrated capsid protein. | Zhejiang University (Hangzhou, PRC) | Chen Q, Shang S, Sheng H, Zhou J | 6/7/2006 | 10/17/2007 |
WO 2007114337 | An immune agglutination reagent kit comprising two monoclonal antibodies with different epitopes immobilized on two types of sensitized carrier particle; useful for measuring the amount of carbohydratedeleted transferrin in a test substance. | Nissui Pharmaceutical Co. (Tokyo) | Natsubayashi T, Takano A, Terunuma I | 3/31/2006 | 10/11/2007 |
US 20070190585 | Analyzing biological material comprising individualspecific antibodies, comprising contacting an array with a sample of biological material to bind at least a portion of the individual-specific antibodies to the multiple antigens of the array to form immune complexes, and detecting the immune complexes by the application to the array of at least three separate antibodies. | Apel WA, Thompson VS | Apel WA, Thompson VS | 5/10/2001 | 8/16/2007 |
