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Detection and sizing of telomeric repeat DNA in situ

Nature Biotechnology volume 17, pages 200–201 (1999)Cite this article

Abstract

A performance comparison of PRINS and PNA assays.

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Figure 1: Staining of telomeric repeats in human lymphocyte chromosomes from a healthy donor by PRINS or by FISH with PNA probes.

References

  1. Koch, J. et al. 1989. Chromosoma 98:259– 265.

    Article  CAS  Google Scholar 

  2. Therkelsen, A.J. et al. 1995. Cytogenet. Cell Genet. 68:115–118.

    Article  CAS  Google Scholar 

  3. Koch, J. 1999. In Nonradioactive labeling and detection of biomolecules, Edn. 2. Kessler, C. (ed.). Springer–Verlag, New York, in press.

    Google Scholar 

  4. Pinkel, D. et al. 1986. Proc. Natl. Acad. Sci. USA 83: 2934–2938.

    Article  CAS  Google Scholar 

  5. Lansdorp, P.M. et al. 1996. Hum. Mol. Genet. 5: 685–691.

    Article  CAS  Google Scholar 

  6. Krejci, K. and Koch, J. 1999. Chromosoma 107:198–203.

    Article  Google Scholar 

  7. Koch, J. et al. 1995. Cytogenet. Cell Genet. 71: 142–147.

    Article  CAS  Google Scholar 

  8. Slijepcevic, P. and Bryant, P.E. 1995 . Cytogenet. Cell Genet. 69:87– 89.

    Article  CAS  Google Scholar 

  9. Slijepcevic, P. et al. 1997. Chromosoma 106: 413–421.

    Article  CAS  Google Scholar 

  10. Goss, S.J. and Harris, H. 1977. J. Cell Sci. 25:17.

    CAS  PubMed  Google Scholar 

  11. Waldren, C. et al. 1984. Cytometry 5:584 –588.

    Article  CAS  Google Scholar 

  12. Lee, T.N.H. and Singer, M.F. 1982. J. Mol. Biol. 161:323–342.

    Article  CAS  Google Scholar 

  13. Azzalin, C.M. et al. 1997. Cytogenet. Cell Genet. 78: 112–115.

    Article  CAS  Google Scholar 

  14. Moyzis, R.K. et al. 1988. Proc. Natl. Acad. Sci. USA 85: 6622–6626.

    Article  CAS  Google Scholar 

  15. de Lange, T. 1995. pp. 264–293 in Telomeres. Blackburn, E.H. and Greider, C.W. (eds.). Cold Spring Harbor Laboratory Press, Cold Spring Harbor, NY.

  16. Koch, J. et al. 1991. GATA 8:171– 178.

    CAS  Google Scholar 

  17. Zijlmans, J.M. et al. 1997. Proc. Natl. Acad. Sci. USA 94:7423–7428.

    Article  CAS  Google Scholar 

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Authors and Affiliations

  1. senior researcher in the department of cytogenetics, Danish Cancer Society, Tage Hansens Gade 2 , Aarhus C, DK–8000, Denmark

    Jørn Koch

  2. department of cytogenetics, Danish Cancer Society,

    Nedime Serakinci

  3. department of medical biology, Marmara University, Turkey

    Nedime Serakinci

Authors
  1. Nedime Serakinci
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  2. Jørn Koch
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Serakinci, N., Koch, J. Detection and sizing of telomeric repeat DNA in situ. Nat Biotechnol 17, 200–201 (1999). https://doi.org/10.1038/6209

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