Abstract
A physicomathematical approach to decoding the relationship between amino acid sequence and protein function may provide a novel way of designing biologically active peptides
This is a preview of subscription content, access via your institution
Access options
Subscribe to this journal
Receive 12 print issues and online access
$259.00 per year
only $21.58 per issue
Buy this article
- Purchase on SpringerLink
- Instant access to the full article PDF.
USD 39.95
Prices may be subject to local taxes which are calculated during checkout
Similar content being viewed by others
References
Kanochisa, M. 1988. A multivariant analysis method for discriminating protein secondary structural segments. Protein Engineering 2: 87–92.
Nakai, K., Kidera, A., and Kanechisa, M. 1988. Cluster analysis of amino acid indices for prediction of protein structure and function. Protein Engineering 2: 93–100.
Cosic, I. 1994. Macromolecular bioactivity: Is it resonant interaction between macromolecules?-Theory and applications. IEEE Transactions on Biomedical Engineering 41 12: 1101–1114.
Cosic, I.M., and Vojisavljevic, V. 1989. Prediction of “hot spots” in interleukin-2. based on informational spectrum, characteristics of growth regulating factors. Biochimie 3: 333–342.
Cosic I. and Hearn, M.T. 1991. “Hot spot” amino acid distribution in Ha-ras oncogene product p21: relationship to guanine binding site. J. Molecular Recognition 4: 57–62.
Cosic, I. and Nesic, D. 1988. Prediction of “hot spots” in SV40 enhancer and relation with experimental data. Eur. J. Biochem. 170: 247–252.
Cosic, I., Drummond, A.E., Underwood, J.R. and Hearn, M.T.W. 1994. A new approach to growth factor analogue design: modelling of FGF analogues. Molecular and Cellular Biochem. 130: 1–9.
Krsmanovic, V., Cosic, I., Biquard, J.M., and Hearn, M.T.V. 1993. Artificial peptides and induced antibodies. Patent number WO93/17108.
Author information
Authors and Affiliations
Rights and permissions
About this article
Cite this article
Cosic, I. Virtual Spectroscopy for Fun and Profit. Nat Biotechnol 13, 236–238 (1995). https://doi.org/10.1038/nbt0395-236
Issue date:
DOI: https://doi.org/10.1038/nbt0395-236
This article is cited by
-
Analysis of Tumor Necrosis Factor Function Using the Resonant Recognition Model
Cell Biochemistry and Biophysics (2016)
-
A bioactive peptide analogue for myxoma virus protein with a targeted cytotoxicity for human skin cancer in vitro
Journal of Biomedical Science (2012)
-
Bioactive peptide design using the Resonant Recognition Model
Nonlinear Biomedical Physics (2007)


