Genetically engineered bacteria made biotech drugs possible. Now, they are becoming drugs in their own right, Monya Baker reports.
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References
Steidler, L. et al. Treatment of murine colitis by Lactococcus lactis secreting interleukin-10. Science 289, 1352–1355 (2000).
Steidler, L. et al. Biological containment of genetically modified Lactococcus lactis for intestinal delivery of human interleukin 10. Nat. Biotechnol. 21, 1785–1789 (2003).
Nemunaitis, J. et al. Pilot trial of genetically modified, attenuated Salmonella expressing the E. coli cytosine deaminase gene in refractory cancer patients. Cancer Gene Ther. 10, 737–744 (2003).
Brockstedt, D.G. et al. L. monocytogenes-based cancer vaccines that segregate immunogenicity from toxicity. Proc. Natl. Acad. Sci. USA 101, 13832–13837 (2004).
Agrawal, N. et al. Bacteriolytic therapy can generate a potent immune response against experimental tumors. Proc. Natl. Acad. Sci. USA 101, 15172–15177 (2004).
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Baker, M. Better living through microbes. Nat Biotechnol 23, 645–647 (2005). https://doi.org/10.1038/nbt0605-645
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DOI: https://doi.org/10.1038/nbt0605-645
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