Table 1 Recent patent applications in genomic assays
Patent number | Description | Assignee | Inventor | Priority application date | Publication date |
|---|---|---|---|---|---|
WO 2008003100, EP 2038074 | A method for functionalizing a surface with sites to form, e.g., a peptide array for protein detection, involving attaching two sets of molecules of predetermined concentrations to sites and treating density-variation surface sites with reactive molecules. | Gao X, Hong A, Yu P, Zhang X, Zhou X, Zhu Q | Gao X, Hong A, Yu P, Zhang X, Zhou X, Zhu Q | 6/29/2006 | 1/3/2008, 3/25/2009 |
WO 2009021141 | A method for designing a microarray for DNA methylation analysis comprises generating probe sequences corresponding to the CpG islands and generating discrete genomic regions. | Johns Hopkins University (Baltimore, MD, USA) | Feinberg A, Irizarry R | 8/7/2007 | 2/12/2009 |
WO 2008034622 | A method of detecting and/or quantifying expression of a target protein that permits target identification without the need for complex biochemical assays, thus serving as a genome-wide approach for target identification. | Pasteur Institute Korea (Seoul) | Emans N, Nehrbass U | 9/20/2006 | 8/21/2008 |
US 20080064040 | A new assay panel comprising fluorescence or luminescence assays; useful for the detection of gene or protein silencing, gene or protein inactivation, or gene or protein activation in an intact cell. | Odyssey Thera (San Ramon, CA, USA) | Belisle B, Lamerdin JE, MacDonald ML, Watson MSW, Westwick JK | 5/30/2003 | 3/13/2008 |
WO 2007070560, EP 1977005 | A method of identifying an imprinted gene comprising analyzing the chromatin structure of the subject's genome to establish a map of the subject's chromatin structure. | Bjornsson HT, Nimblegen Systems (Madison, WI, USA), Feinberg AP, Green RD | Bjornsson HT, Feinberg AP, Green RD | 12/13/2005 | 8/23/2007 |
WO 2005020886, US 20060111848 | A computational method for identifying proteins in a pathogen suitable as a target to detect a therapeutic agent, by determining a computationally phenotypic change in the pathogen by loss of proteins and identifying the ranking order of proteins. | New England Biolabs (Ipswich, MA, USA) | Carlow CKS, Foster J, Kumar S, Zhang Y | 6/27/2003 | 3/10/2005, 5/25/2006 |
US 20040241636, WO 2005001115 | Annotating gene or protein function by measuring, for example, the quantity of a test protein in the first and second population of cells contacted with a test or control reagent, comparing results and identifying the proteins linked to the test gene or protein. | Belisle B, Lamerdin JE, MacDonald ML, Michnick SWW, Odyssey Thera (San Ramon, CA, USA), Westwick JK | Belisle B, Lamerdin JE, MacDonald ML, Michnick SWW, Westwick JK | 5/30/2003 | 12/2/2004, 1/6/2005 |
WO 2003064701, EP 1470254 | Identifying a reliable diagnostic, prognostic or staging marker for phenotypic conditions characterized by altered DNA methylation, for example, cancer, comprising obtaining a set of at least two biological samples in each case having genomic DNA. | Epigenomics (Berlin) | Schweikhardt RG, Sledziewski AZ | 1/30/2002 | 8/7/2003, 10/27/2004 |
US 20040115722 | A method of producing a biopolymeric array useful for diagnostic or screening procedures or in gene expression analysis, comprising immobilizing different probes for respective targets on a solid support. | Caren MP, Corson JF, Kronick M, Leproust EM, Peck BJ | Caren MP, Corson JF, Kronick M, Leproust EM, Peck BJ | 10/25/2002 | 6/17/2004 |
WO 2004015080 | A method of detecting alternative splicing of a first target sequence comprising hybridizing probes to target sequences without prior amplification to form hybridization complexes; useful in diagnostic medicine. | Illumina (San Diego, CA, USA), Regents of the University of California (Oakland, CA, USA) | Fan J, Fu X | 8/9/2002 | 2/19/2004 |
