Table 1 Characteristics of issued iPS cell patents

From: Pluripotent patents make prime time: an analysis of the emerging landscape

Patent no.

Earliest priority;filing date;grant date

Composition/ product claims

Process claims

Listed genes in broadest claims

Related international publications

JP 2008-131577 (Yamanaka)

Dec. 13, 2005;Dec. 6, 2006;Sept. 12, 2008

No

Yes

Oct 3/4, Klf4, c-Myc and Sox2.

EP1970446, ZA200804673, US20090068742, KR20080095852, JP2009165480, JP2009165479, JP2009165478, JP2008283972, JP4183742, JP2009165481, WO2007069666, EA200870046, CN101356270, CA2632142, AU2006325975, US20090227032, US20090047263, US20100062533

GB2450603 (Sakurada)

June 15, 2007;June 13, 2008;Jan. 12, 2010

No

Yes

Combination of Oct3/4, Klf4 and Sox2 (but not c-Myc)

US20090304646, US20090191159, JP2008307007, WO2009007852, WO2009006997, WO2009006930, AU2008273817

US 7,682,828 (Jaenisch)

Nov. 26, 2003;Nov. 24, 2004;March 23, 2010

Yes

No

Endogenous gene expressed in pluripotent ES cell, required for pluripotency, and downregulated during differentiationExogenous nucleic acid encoding pluripotency protein expressed in pluripotent ESC and downregulated during differentiation

International publications with this priority date not foundWO2008124133 (earliest priority claim April 7, 2007)