Table 1 Recent patent applications in drug discovery
Patent number | Description | Assignee | Inventor | Priority application date | Publication date |
---|---|---|---|---|---|
WO 2010083617 | New pyrazolopyrimidine compounds that are protein kinase inhibitors; useful for treating (hyper) proliferative diseases and angiogenesis-related diseases or as a research tool in drug discovery. | Oncalis (Schlieren, Switzerland) | Capraro H | 1/21/2009 | 7/29/2010 |
JP 2010164448 | A dispensing apparatus used in genome-based drug discovery, with an overflow tank to temporarily accommodate cleaning liquid overflowing through an opening from the liquid storage tank storing cleaning liquid for the nozzle cleaning portion. | Matsushita Electrical Industrial (Kadoma, Japan) | Shimokawa K, Yamashita S | 1/16/2009 | 7/29/2010 |
US 20100167418 | A method of identifying a candidate modulator of integrin activity, comprising contacting integrin polypeptide with candidate agent and detecting binding of candidate agent to the integrin polypeptide. | Immune Disease Institute (Boston) | Luo BH, Springer TA | 12/29/2008 | 7/1/2010 |
WO 2010073519 | A new Alzheimer's disease model animal having a continuous increase in the concentration of amyloid-β protein in the brain; useful for monitoring in vivo production of amyloid-β protein or symptoms of Alzheimer's disease and in drug discovery. | Japan Health Science Foundation (Tokyo) | Kagawa S, Takikawa O | 12/26/2008 | 7/1/2010 |
US 20100152280 | A new oligomeric compound that is a modulator of systemic RNA interference defective-1 expression; useful for diagnosing and treating cancer and viral infection, and in drug discovery. | Isis Pharmaceuticals (Carlsbad, CA, USA) | Bennett CF, Dobie KW | 5/24/2004 | 6/17/2010 |
WO 2010060019, US 20100130725 | A method of characterizing a molecule, comprising collecting the biosensor response of a molecule producing a primary profile, collecting the biosensor response of a marker panel in a cell panel, extracting a specific set of biosensor parameters from each biosensor signal, normalizing each biosensor parameter against a positive control and comparing the molecule biosensor index to a library of modulator biosensor indexes. | Corning (Corning, NY, USA) | Fang Y, Ferrie AM, Lahiri J, Tran E | 11/24/2008 | 5/27/2010, 5/27/2010 |
US 20100122906 | A biochemical concentrator for drug discovery comprising a solution containing a target species, and an electric field generator for effecting movement of the target species within the solution and changing species flux within regions of solution. | Holm-Kennedy JW | Holm-Kennedy JW | 3/16/2005 | 5/20/2010 |
US 20100119413 | A system for analyzing biological samples in a microtiter plate for drug discovery research; comprises a processor that controls a gripper assembly to grip the microtiter plate along opposing sides in portrait or landscape orientation. | Beckman Coulter (Fullerton, CA, USA) | Avgerinos PN, Rizzotte SH, Turner DA | 5/18/2008 | 5/13/2010 |
US 20100099190 | A cultured cell construct comprising spheroids of mesenchymal stem cells; useful for developing biodevices used for diagnosis, reconstructive medicine and drug discovery. | Transparent (Chiba, Japan) | Chung U, Itaka K, Kataoka K, Nishiyama N, Ohba S, Wang W, Yamasaki Y | 10/21/2008 | 4/22/2010 |
JP 2010071851 | A flowthrough cell-type biosensor apparatus for use in, e.g., drug discovery. The biosensor has a switching valve with a suction element that maintains the pump in an airtight state when sucking the sample solution from a container using the pump. | Ulvac (Chigasaki, Japan) | Ito A, Mizutani T, Take R, Tanaka S | 9/19/2008 | 4/2/2010 |
JP 2010051243 | A new Actinomyces strain deposited as NITE P-621 and obtained by introducing a mycinose biosynthetic gene into the bacteria; useful for manufacturing a rosamicin derivative having antimicrobial activity and for drug discovery. | Sansho (Osaka, Japan) | Anzai Y, Fujiwara T, Iisaka Y, Kato F, Kinoshita K, Moroboshi T | 8/28/2008 | 3/11/2010 |