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Curagen lays down markers, 120,000 of them

Nature Biotechnology volume 17, page 951 (1999)Cite this article

In mid-August, Curagen Corporation (New Haven, CT) announced it had identified more than 55,000 new single-nucleotide polymorphisms (SNPs) from its work in resequencing human expressed sequences. The company heralded the announcement as a "landmark discovery." Investors were pleased: the company's stock price rose around a third on the news. At the same time, the market's appreciation of Genset, another SNP company, continues to be subdued.

Following this most recent work, Curagen now has a database of over 120,000 SNPs from expressed regions (copy SNPs or cSNPs) of the human genome. Richard Shimkets, the company's director of internal discovery, says that this represents around 25% of the cSNPs that are most relevant to human medicine. He thinks that the cSNPs are already generating value for Curagen. "We believe that we can get intellectual property protection on the sequences per se. We have been aggressive in making patent filings on cSNPs."

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  1. John Hodgson

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Hodgson, J. Curagen lays down markers, 120,000 of them. Nat Biotechnol 17, 951 (1999). https://doi.org/10.1038/13643

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