Covalent modification of DNA by methylation is crucial for maintaining the stability and structure of chromatin. Reports of the effects that altered methylation has for cancer development stress the importance of balanced genomic methylation.
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Hsieh, CL., Jones, P. Meddling with methylation. Nat Cell Biol 5, 502–503 (2003). https://doi.org/10.1038/ncb0603-502
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DOI: https://doi.org/10.1038/ncb0603-502