Regulation of Gene Expression
Edited by:
- K. E. Chapman &
- S. J. Higgins
Portland Press May 2001 Paperback £19/$30
Since the recent completion of several eukaryotic and prokaryotic genome-sequencing projects, today's molecular geneticists and cell biologists are faced with studies that seek to explain how the expression of their gene(s) of interest is regulated in a specific and timely fashion. Regulation of Gene Expression can be recommended for all those who intend to study the subject in more detail. By choosing leading experts in different areas of transcriptional regulation, the editors have provided the reader with a stimulating summary of the current state of research. In addition to explaining most basic mechanisms of transcriptional regulation, the book illustrates how this regulation is involved in central biological processes such as cell division, death and differentiation. Furthermore, consequences of transcriptional deregulation (for example cancer) are used as examples to show the relevance of transcriptional regulation for the understanding and the potential treatment of common diseases. The book provides an excellent link between textbooks and the current status of original publications. At the end of most chapters the main open questions in the respective areas are provided.
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