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Aurora A in cell division: kinase activity not required

Aurora A kinase is a key regulator of cell division, whose functions were attributed to its ability to phosphorylate diverse substrates. Aurora A is now shown to have a kinase-independent role in the regulation of chromatin-mediated microtubule assembly.

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Figure 1: Localization and function of kinase-active and kinase-inactive AIR-1.

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Correspondence to Monica Gotta.

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Kress, E., Gotta, M. Aurora A in cell division: kinase activity not required. Nat Cell Biol 13, 638–639 (2011). https://doi.org/10.1038/ncb2276

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