Supplementary Figure 5: Lgr5 and Troy co-FISH in the adult ovary. | Nature Cell Biology

Supplementary Figure 5: Lgr5 and Troy co-FISH in the adult ovary.

From: Lgr5 marks stem/progenitor cells in ovary and tubal epithelia

Supplementary Figure 5

Co-FISH of Lgr5 and Troy on adult wild-type ovary sections, demonstrating enriched Troy mRNA expression in Lgr5+ OSE cells. Bright white dots represent positive FISH signals. OSE cells are denoted above yellow dashed lines. Note similar expression profile of Troy to that of Lgr5, with abundant transcripts present in OSE cells around a follicle but absent atop a corpus luteum. RNase A-treated sections revealed specificity of Lgr5 and Troy transcripts. F, follicle; CL, corpus luteum. Scale bars: 10 μm.

Back to article page