Supplementary Figure 2: Annotated alignment of deduced full-length zebrafish Lkt/ABCC4 protein with orthologs in other species. | Nature Cell Biology

Supplementary Figure 2: Annotated alignment of deduced full-length zebrafish Lkt/ABCC4 protein with orthologs in other species.

From: Prostaglandin signalling regulates ciliogenesis by modulating intraflagellar transport

Supplementary Figure 2

Black: identical across four species. Grey: identical in 2 or more species or conservative amino acid substitution. IDs: human (NP005836), mouse (NP001028508), chicken (NP001025990) and zebrafish (EU586042). TM: transmembrane domain. NBD: nucleotide binding domain. Red star: leakytail zebrafish mutation site (T804M). Walker A/B (ATP-binding sites) and signature C are conserved motifs found within the NBD of ABC transporters.

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