Supplementary Figure 6: TNF and Dex induce binding of GR to specific loci.

(a) Genomic distribution of significantly enriched GR peaks. (b) Mean mammalian conservation scores of GR peak subsets centered around GR peak centers. The gray dotted line represents mean conservation score across entire genome. (c) Heat map showing SQRT –log₂ (p-value) comparing the fold change in expression for the nearest gene from peak sets at the indicated condition/time point to a random set of H3K27ac peaks (fold changes are provided in Fig. 5c). Non-significant p-values after multiple testing hypothesis correction are labeled N.S.