Supplementary Figure 8: AKT2 is not required for the normal development of white adipose tissue.
From: Rapid depot-specific activation of adipocyte precursor cells at the onset of obesity
(A-B) Confocal images (A) of developing wild-type and Akt2−/− SWAT stained with LipidTOX (a lipid stain) and Isolectin IB4 (an endothelial cell stain) and (B) corresponding lipid droplet size quantification based on LipidTOX staining (n = 3 mice for all groups except n = 4 mice for Akt2−/−P5). Each group includes mice from 2-3 different litters. (C) Echo MRI quantification of fat mass from the indicated groups of mice at 6 weeks of age. (n = 13 mice for Akt2fl/fl and n = 14 mice for PdgfRα-cre; Akt2fl/fl). Scale bars in (A) are 50 μm. Error bars represent mean ± s.e.m. PX indicates postnatal day X.
