Supplementary Figure 4: Frequency of cell divisions and alignment of cell division axes. | Nature Cell Biology

Supplementary Figure 4: Frequency of cell divisions and alignment of cell division axes.

From: Myosin-II-mediated cell shape changes and cell intercalation contribute to primitive streak formation

Supplementary Figure 4

(a) Number of cell divisions in the four domains shown in figure 4a as a function of time, showing that cell doubling times in all domains are similar (∼6 h). (b) Number of cell divisions as a function of time of the embryo shown in C. (c) Histograms showing the distributions of the cell division axes occurring in domains in different parts of the embryo. Initially the cell divisions axes in the posterior parts of the embryo are aligned perpendicular to the midline of the embryo (0–4.3 h). From 4.4 h of development onwards this polarity is gradually lost. All histograms contain the total number of divisions occurring over a 2.1 h period in the domain. Scale bar is 200 μm.

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