A total of 58 ITIM receptors were selected based on the criteria that (1) they are plasma membrane receptors and (2) they use ITIM as the main signalling motifs. Data were obtained from the TCGA AML database (
https://tcga-data.nci.nih.gov/tcga; accessed November 5, 2012), and expression was normalized to
GADPH expression, Affymetrix housekeeping gene expression, or total mRNA. For
lair1, the overall survival of AML patients younger than 65 years old were analysed (
n = 58 samples for higher and
n = 58 samples for lower). In all other cases, patients were separated into two groups based on whether they had higher (
n = 82 samples) or lower (
n = 83 samples) than the average expression levels of the indicated genes (
n = 165 samples).
