Supplementary Figure 2: Stage-specific zipping architecture. | Nature Cell Biology

Supplementary Figure 2: Stage-specific zipping architecture.

From: Quantitative analysis of cytoskeletal reorganization during epithelial tissue sealing by large-volume electron tomography

Supplementary Figure 2

(A) Characteristic view of initial adhesion junctions. The insert shows a magnified view of putative cadherin densities, which are obliquely oriented and visible as thin lines (white arrows) lying in the extracellular space of the contact areas. (B) Schematic representation of cell membrane organization and cytoskeletal remodelling of the LE cells during early (yellow), mid (green) and late zipping (blue), and after zipping is completed (grey). The respective number of LE cells occupying the different zipping phases of three anterior (ant 1–3) and one posterior (post 1) zipping event, are shown in the lower halve.

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