Supplementary Figure 6: DNA binding strength and DNA binding motifs of all Myc and E2f3 peaks.
From: Redeployment of Myc and E2f1–3 drives Rb-deficient cell cycles
(a) Tag intensity plots (tags per bp per peak per 100M reads) around all peak summits identified in crypts and villi, as indicated. (b) Canonical DNA binding motifs (TTCCCGCC motif for E2f3, underlined with blue lines; CACGTG motif for Myc, underlined with reds lines) or strongest non-canonical motifs identified from all peak sequences in indicated genomic regions. Data in this figure are derived from pooled crypts (n = 32 mice for control, n = 27 mice for Rb KO) or villi (n = 7 mice for control, n = 7 mice for Rb KO).
