Supplementary Figure 9: Impact of mKitL depletion on thymic stromal cell and thymic progenitor populations.
From: A dynamic niche provides Kit ligand in a stage-specific manner to the earliest thymocyte progenitors
(a) Relative percentage of phenotypic TECs, VECs and MCs from 4–5 weeks old control, Foxn1ΔEx7 and Tie2/PdgfbΔEx7 mice analyzed as in Fig. 5a. Number of biological replicates displayed. Error bars show standard errors. No statistically significant differences were observed. For source data see Supplementary Table 5. (b) Absolute number of DN, DP, SP4 and SP8 from 4–5 week old control (n = 7) and Foxn1ΔEx7 mice (n = 3). Error bars show standard errors. P-values relative to the control group are shown. For source data see Supplementary Table 5. (c) Absolute number of phenotypic DN, DP, SP4 and SP8 from 4–5 weeks old control (n = 5), Tie2/PdgfbΔEx7 (n = 4) and Tie2/Pdgfb/FoxN1ΔEx7 (n = 5), analyzed as in Fig. 5a. Error bars show standard errors. P-values relative to the control group are shown. For source data see Supplementary Table 5.
