Supplementary Figure 7: Models for modular and quantitative control of MyoII activation. | Nature Cell Biology

Supplementary Figure 7: Models for modular and quantitative control of MyoII activation.

From: Modular activation of Rho1 by GPCR signalling imparts polarized myosin II activation during morphogenesis

Supplementary Figure 7

Localised inputs derive from striped ectoderm (orange) and ventral mesoderm (purple) expressed transcription factors in blastoderm embryos (top). Mesoderm and endoderm patterning relies on Fog and possibly other ligands signalling via multiple, localised (e.g. Mist) or ubiquitous (e.g. Smog) GPCRs, which relay information to G proteins α,β andγ. T48 and Tolls are single pass transmembrane proteins.

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