Supplementary Figure 4: Characterisation of squamous cell carcinomas.
From: A single dividing cell population with imbalanced fate drives oesophageal tumour growth
(a,b) Cryosections stained for KRT14 (a) or LOR (b, green). KRT4 is magenta, ITGA6 white and DAPI blue. Scale bars, 200 μm and 100 μm, respectively. Images are representative of 3 tumours. (c) ErbB signaling pathway based on Kegg pathway analysis (http://www.genome.jp/kegg/kegg3a.html). The colour indicates the logarithmic fold changes of gene expression between SCC and HGD, boxes are gene products, + p protein interaction via phosphorylation, solid line direct protein-protein interaction, dashed line: indirect interaction, arrows indicate activation, T ended lines inhibition.
