Supplementary Figure 2: Characterisation of KPC vs. KPCZ tumours. | Nature Cell Biology

Supplementary Figure 2: Characterisation of KPC vs. KPCZ tumours.

From: The EMT-activator Zeb1 is a key factor for cell plasticity and promotes metastasis in pancreatic cancer

Supplementary Figure 2

Representative images of immunohistochemical and histological stainings of KPC and KPCZ tumours and quantifications of the indicated markers are given. Asterisks label Zeb1-expressing stroma cells in KPCZ tumours. Specific blue MTS staining labels collagen fibres. Scale bars, 100 μm, for lower left image 50 μm. n = 48 KPC, 29 KPCZ independent tumours for Zeb1 and MTS; n = 15 independent tumours for KPC, 13 independent tumours for KPCZ for all other markers, error bars show mean ± S.D.; ∗∗∗∗p < 0.0001, n.s. = not significant, Chi-square test (two-tailed) for Zeb1, E-cadherin and Sox2, unpaired Student’s t-test (two-tailed) for Ki67 and Casp3 (with Welch’s correction), Mann-Whitney test (two-tailed) for ECM and CD31.

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